Perioperative medicine & outcomes

Cognitive prehabilitation in surgical patients: a scoping review

Br J AnaesthPublished Scoping review of randomised controlled trials

Authors' conclusion

Cognitive prehabilitation trials consistently evaluate multidomain, computerised brain training, and, with high adherence, efficacy is evident.

Study context

Population
Adults undergoing surgery enrolled in RCTs of cognitive prehabilitation
Participants
833 adults · 8 trials
Comparison
Cognitive prehabilitation
Methodological detailsregistered protocol, peer-reviewed search strategy, duplicate, independent review, narrative synthesis, MEDLINE, Embase, CINAHL, PsycINFO, Web of Science and Cochrane CENTRAL searched from inception to 04/2025
  • Registered protocol
  • Peer-reviewed search strategy
  • Duplicate, independent review
  • Narrative synthesis
  • MEDLINE, Embase, CINAHL, PsycINFO, Web of Science and Cochrane CENTRAL searched from inception to 04/2025

Primary result

As reported in the abstract

Delirium and postoperative neurocognitive disorders (trials with high adherence)

Significant reduction in delirium in two trials with high adherence (absolute risk reduction)

9.8%-15.9%

Significant reduction in postoperative neurocognitive disorders in two trials with high adherence (absolute risk reduction)

20.2%-36.8%

Original publication

Cognitive prehabilitation in surgical patients: a scoping review. Br J Anaesth. Published 11 July 2026. doi:10.1016/j.bja.2026.05.016

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