Perioperative medicine & outcomes

Outcomes reported in randomised trials of surgical prehabilitation: a scoping review

Br J AnaesthPublished Scoping review of randomised controlled trials

Authors' conclusion

There is substantial heterogeneity in the reporting of outcomes and assessment tools across surgical prehabilitation trials.

Study context

Population
RCTs of unimodal or multimodal prehabilitation (nutrition, exercise, psychological support) lasting ≥7 days in adults undergoing elective surgery
Participants
76 trials
Primary endpoint
Outcomes and assessment tools used in surgical prehabilitation trials
Methodological detailsMEDLINE, EMBASE, PsychInfo, Web of Science, CINAHL and Cochrane searched February 2023, Outcomes classified by the International Society for Pharmacoeconomics and Outcomes Research framework
  • MEDLINE, EMBASE, PsychInfo, Web of Science, CINAHL and Cochrane searched February 2023
  • Outcomes classified by the International Society for Pharmacoeconomics and Outcomes Research framework

Primary result

As reported in the abstract

Outcomes and assessment tools reported
Different outcomes identified
50
Outcome assessment tools
184
Observer-reported outcomes (most commonly hospital LOS), trials
86% (n=65)
Performance outcomes (most commonly exercise capacity by cardiopulmonary exercise testing), trials
80% (n=61)
Clinician-reported outcomes (most frequently postoperative complications, Clavien-Dindo), trials
78% (n=59)
Patient-reported outcomes (most often health-related quality of life, SF-36 or SF-12), trials
76% (n=58)
Biomarker outcomes (most commonly inflammatory markers, C-reactive protein), trials
16% (n=12)

Original publication

Outcomes reported in randomised trials of surgical prehabilitation: a scoping review. Br J Anaesth. Published 3 April 2024. doi:10.1016/j.bja.2024.01.046

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