Perioperative medicine & outcomes
Outcomes reported in randomised trials of surgical prehabilitation: a scoping review
Authors' conclusion
There is substantial heterogeneity in the reporting of outcomes and assessment tools across surgical prehabilitation trials.
Study context
- Population
- RCTs of unimodal or multimodal prehabilitation (nutrition, exercise, psychological support) lasting ≥7 days in adults undergoing elective surgery
- Participants
- 76 trials
- Primary endpoint
- Outcomes and assessment tools used in surgical prehabilitation trials
Methodological detailsMEDLINE, EMBASE, PsychInfo, Web of Science, CINAHL and Cochrane searched February 2023, Outcomes classified by the International Society for Pharmacoeconomics and Outcomes Research framework
- MEDLINE, EMBASE, PsychInfo, Web of Science, CINAHL and Cochrane searched February 2023
- Outcomes classified by the International Society for Pharmacoeconomics and Outcomes Research framework
Primary result
As reported in the abstract
Outcomes and assessment tools reported
- Different outcomes identified
- 50
- Outcome assessment tools
- 184
- Observer-reported outcomes (most commonly hospital LOS), trials
- 86% (n=65)
- Performance outcomes (most commonly exercise capacity by cardiopulmonary exercise testing), trials
- 80% (n=61)
- Clinician-reported outcomes (most frequently postoperative complications, Clavien-Dindo), trials
- 78% (n=59)
- Patient-reported outcomes (most often health-related quality of life, SF-36 or SF-12), trials
- 76% (n=58)
- Biomarker outcomes (most commonly inflammatory markers, C-reactive protein), trials
- 16% (n=12)
Original publication
Outcomes reported in randomised trials of surgical prehabilitation: a scoping review. Br J Anaesth. Published 3 April 2024. doi:10. 1016/ j. bja. 2024. 01. 046
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