Cardiac arrest & resuscitation

Comparing outcomes of out-of-hospital cardiac arrest patients with initial shockable rhythm in Singapore and Osaka using population-based databases

Crit CarePublished Secondary analysis of two population-based out-of-hospital cardiac arrest (OHCA) databases

Authors' conclusion

This study showed the outcomes of OHCA patients without prehospital ROSC in Singapore were worse than expected derived from Osaka data even using population-based databases.

Study context

Population
Adult OHCA patients with initial shockable rhythm
Participants
2,905 vs 3,088
Comparison
Singapore vs Osaka
  • Singaporen = 2,905
  • Osakan = 3,088reference
Primary endpoint
Good neurological outcomes:
  • OE ratio
  • Singapore observed vs expected from Osaka
Follow-up
one-month
Methodological detailsmachine-learning-based prediction model, observed-expected ratio, subgroups by prehospital ROSC
  • Machine-learning-based prediction model
  • Observed-expected ratio
  • Subgroups by prehospital ROSC

Primary result

As reported in the abstract

One-month good neurological outcome, by prehospital ROSC (subgroup)

OE ratio

1.067

95% CI 1.012–1.125

with prehospital ROSC; adjusted for patient characteristics

OE ratio

0.238

95% CI 0.173–0.294

without prehospital ROSC; adjusted for patient characteristics

Original publication

Comparing outcomes of out-of-hospital cardiac arrest patients with initial shockable rhythm in Singapore and Osaka using population-based databases. Crit Care. Published 6 December 2023. doi:10.1186/s13054-023-04771-5

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