Cardiac arrest & resuscitation
Modeling the Cost-Effectiveness of Incorporating Extracorporeal Cardiopulmonary Resuscitation Strategy in Out-of-Hospital Cardiac Arrest Patients
Authors' conclusion
In this modeling study, adopting an ECPR strategy for OHCA in Singapore was likely to be cost-effective across different age-based eligibility thresholds; however, it was sensitive to delays in transport time.
Study context
- Population
- Nontraumatic adult out-of-hospital cardiac arrest (OHCA) patients from Singapore with initial shockable rhythm and no prehospital ROSCOHCA cases analysed
- Participants
- 1,462 patients
- Comparison
- Extracorporeal cardiopulmonary resuscitation (ECPR) strategy vs current practice
- Outcome
- Base-case ICER, ECPR strategy vs current practice (healthcare provider perspective, lifetime horizon)
Methodological detailssimulation-based, decision tree and Markov model, lifetime horizon, healthcare provider perspective
- Simulation-based
- Decision tree and Markov model
- Lifetime horizon
- Healthcare provider perspective
Main finding
As reported in the abstract
ICER
$34,320/QALY
Net monetary benefit
$8,532
Further findings
ICER, age-restricted ECPR strategy (< 65 yr) (scenario analysis)
- ICER similar to base case
- $33,469/QALY
ICER, 10-minute transport extension (scenario analysis)
- ICER slightly exceeded the willingness-to-pay threshold
- $47,158/QALY
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Modeling the Cost-Effectiveness of Incorporating Extracorporeal Cardiopulmonary Resuscitation Strategy in Out-of-Hospital Cardiac Arrest Patients. Crit Care Med. Published 13 May 2026. doi:10.
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