Neuroanesthesia & neurocritical care

Comparison between remimazolam and propofol anaesthesia for interventional neuroradiology: a randomised controlled trial

Anaesth Crit Care Pain MedPublished Randomised controlled trial

Authors' conclusion

Remimazolam anaesthesia showed superior haemodynamic stability compared with propofol anaesthesia during neuroradiology procedures.

Study context

Population
Patients undergoing elective endovascular embolisation (interventional neuroradiology) under GA
Participants
76 patients
Comparison
Continuous remimazolam infusion vs target-controlled propofol infusion
  • Remimazolamn = 38
  • Propofoln = 38reference
Primary endpoint
Total phenylephrine dose during the procedure
Methodological detailssingle-masked, single-centre
  • Single-masked
  • Single-centre

Primary result

As reported in the abstract

P = 0.001

Further findings

Hypotensive events

P = 0.001

OutcomeP value
Recovery times to spontaneous breathing, eye-opening, extubation and orientationall p < 0.001

Recovery times to spontaneous breathing, eye-opening, extubation and orientation

Shorter in the remimazolam group than in the propofol group

Original publication

Comparison between remimazolam and propofol anaesthesia for interventional neuroradiology: a randomised controlled trial. Anaesth Crit Care Pain Med. Published 5 December 2023. doi:10.1016/j.accpm.2023.101337

Composed by AI from the published abstract and checked against it. How Briefs are made →

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