Neuroanesthesia & neurocritical care
Effect of remimazolam vs propofol on emergence from general anesthesia in patients undergoing cerebral endovascular procedures: A randomized controlled, non-inferiority trial
Authors' conclusion
In patients undergoing cerebral endovascular procedures, remimazolam did not increase the time from anesthesia vs propofol.
Study context
- Population
- Adults scheduled for cerebral endovascular procedures129 completed
- Participants
- 142 adults
- Comparison
- Remimazolam vs propofol for GA
- Primary endpoint
- Time to emergence from anesthesia
Methodological detailsprospective, double-blind, non-inferiority, single academic hospital
- Prospective
- Double-blind
- Non-inferiority
- Single academic hospital
Primary result
As reported in the abstract
Secondary outcomes
Vasopressor use during surgery
P < 0.001
Postoperative delirium and Modified Rankin Scale (mRs) · 30 and 90 days after surgery
- No difference between groups
Safety
Hypotension during induction
P = 0.03
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Effect of remimazolam vs propofol on emergence from general anesthesia in patients undergoing cerebral endovascular procedures: A randomized controlled, non-inferiority trial. J Clin Anesth. Published 5 December 2023. doi:10.
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