Comparison between the Rotational Thromboelastometry (ROTEM) Delta device against the Cartridge-based Thromboelastography 6s and Quantra in a healthy third trimester pregnant cohort
Authors' conclusion
All the POCVT devices demonstrated a high correlation to laboratory Clauss fibrinogen, making each beneficial for the early recognition and management of hypofibrinogenemia.
Study context
- Population
- Healthy third trimester pregnant women
- Comparison
- ROTEM Delta vs TEG 6s and Quantra
- Outcome
- Correlation of 3 POCVT devices with laboratory Clauss fibrinogen and platelets
Main finding
As reported in the abstract
Correlation with Clauss fibrinogen
| Group | Value | P |
|---|---|---|
| ROTEM | r 0.76-0.84 | P < 0.0001 |
| TEG6s | r 0.71 | P < 0.0001 |
| Quantra | r 0.72 | P = 0.0001 |
Value
ROTEMr 0.76-0.84
TEG6sr 0.71
Quantrar 0.72
P
ROTEMP < 0.0001
TEG6sP < 0.0001
QuantraP = 0.0001
Further findings
| Outcome | ROTEM | Quantra | Estimate | P value |
|---|---|---|---|---|
| Correlation with laboratory plateletsModerate correlation | r 0.54;0.45 | r 0.66 | ||
| P | P < 0.0001; P = 0.0013 | P = 0.0001 | ||
| Inter-device correlation, fibrinogen parametersTEG6s vs ROTEM · high | r 0.88 | P < 0.0001 | ||
| Inter-device correlation, fibrinogen parametersQuantra vs ROTEM · high | r 0.74 | P < 0.0001 | ||
| Inter-device correlation, platelet parametersQuantra vs ROTEM · moderate | r 0.51 | P = 0.0036 | ||
| Total running timeQuantra vs ROTEM · if warming and pipetting of ROTEM reagents considered | difference (faster) 20.9 min (95% CI −0.2 to 4.7) | P = 0.07 |
Original publication
Comparison between the Rotational Thromboelastometry (ROTEM) Delta device against the Cartridge-based Thromboelastography 6s and Quantra in a healthy third trimester pregnant cohort. J Clin Monit Comput. Published 29 July 2022. doi:10.
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