Platelet parameters in preeclampsia: comparing rotational thromboelastometry and platelet aggregometry with standard laboratory tests
Authors' conclusion
This study has identified thromboelastometry and aggregometry parameters that may be useful in rapidly ruling out a platelet count < 100,000/μL in patients with preeclampsia, a threshold associated with increased risk of neuraxial haematoma.
Study context
- Population
- Pregnant patients with preeclampsia and pregnant controls
- Participants
- 71 vs 57
- Comparison
- ROTEM and platelet aggregometry vs standard laboratory tests
- Preeclampsian = 71
- Pregnant controlsn = 57reference
- Outcome
- Prediction of laboratory platelet count < 100,000/μL by thromboelastometry and platelet aggregometry parameters
Methodological detailspoint-of-care testing, diagnostic accuracy
- Point-of-care testing
- Diagnostic accuracy
Main finding
As reported in the abstract
Prediction of platelet count < 100,000/μL in preeclampsia
| Group | NPV |
|---|---|
| PLTEM (EXTEM A5-FIBTEM A5) | 1.0 |
PLTEM (EXTEM A5-FIBTEM A5)
NPV1.0
Observational data: associations, not effects.
Further findings
Serial testing (repeat at median 11 h)
- Reclassification of neuraxial anaesthesia risk according to platelet count
- 2
- 55 patients with preeclampsia
Original publication
Platelet parameters in preeclampsia: comparing rotational thromboelastometry and platelet aggregometry with standard laboratory tests. Int J Obstet Anesth. Published 6 December 2025. doi:10.
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