Maternal physiological parameters and routine laboratory tests to screen for maternal sepsis: an observational cohort study
Authors' conclusion
This observational cohort study demonstrated that maternal temperature ≥37.5°C (rather than the threshold of 38°C found in most screening tools) may be important in screening patients at risk of developing maternal sepsis.
Study context
- Population
- Pregnant patients considered at risk of obstetric sepsisNov 2020–Dec 2022
- Participants
- 154 patients
- Exposure
- Physiological and routine laboratory variables: infection confirmed vs infection unlikely
- Infection confirmedn = 58
- Infection unlikelyn = 17reference
- Outcome
- Utility of routine clinical variables, including laboratory tests, in screening for maternal sepsis
- Follow-up
- Time of recruitment
Methodological detailssingle-centre, observational
- Single-centre
- Observational
Main finding
As reported in the abstract
Physiological and routine laboratory variables at recruitment, infection confirmed vs infection unlikely · at the time of recruitment
Temperature best discriminator; AUC-ROC
0.82
95% CI 0.70 to 0.94P <0.0001
Optimal temperature threshold
≥37.5°C
Observational data: associations, not effects.
Original publication
Maternal physiological parameters and routine laboratory tests to screen for maternal sepsis: an observational cohort study. Int J Obstet Anesth. Published 10 May 2025. doi:10.
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