Paediatric anaesthesia & critical care
Comparison of Discharge Readiness in Pediatric Patients: Oral Versus Intranasal Preoperative Midazolam Administration
Authors' conclusion
Age, rather than route of midazolam administration, primarily explained differences in PACU discharge readiness among children undergoing tympanostomy.
Study context
- Population
- Children aged 6 months to 10 years undergoing tympanostomy, Nemours Children's Hospital, Central Florida, November 2023–November 2024
- Participants
- 463 children
- Exposure
- Intranasal vs oral preoperative midazolam
- Intranasaln = 141
- Oraln = 322reference
- Outcome
- PACU LOS (PACU arrival to discharge by standard hospital criteria)
Methodological detailsretrospective chart review, single-centre
- Retrospective chart review
- Single-centre
Main finding
As reported in the abstract
PACU LOS
Intranasal vs Oral: P = 0.02 · Intranasal vs Oral: P = 0.15
Observational data: associations, not effects.
Further findings
Age · significantly younger
P < 0.001
Original publication
Comparison of Discharge Readiness in Pediatric Patients: Oral Versus Intranasal Preoperative Midazolam Administration. Paediatr Anaesth. Published 15 July 2026. doi:10.
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