Comparison of pericapsular nerve group and lateral quadratus lumborum blocks on cumulative opioid consumption after primary total hip arthroplasty: a randomized controlled trial
Authors' conclusion
While both lateral QLB and PENG block+LFC block are effective analgesic methods for patients undergoing THA, patients receiving lateral QLB had decreased cumulative opioid consumption from 36 to 72 hours postoperative and lower pain scores with movement compared with patients receiving PENG+LFC blocks.
Study context
- Population
- Patients scheduled for elective primary total hip arthroplasty101 analysed
- Participants
- 106 patients
- Comparison
- Lateral quadratus lumborum block (QLB) vs pericapsular nerve group (PENG) block + lateral femoral cutaneous nerve block
- QLBn = 51
- PENGn = 50reference
- Primary endpoint
- Postoperative cumulative opioid consumption measured over time
- Follow-up
- Up to 72 hours
Methodological detailssuperiority, Standardized perioperative analgesic protocols
- Superiority
- Standardized perioperative analgesic protocols
Primary result
As reported in the abstract
Mean difference at 36 h
18.0
95% CI 0.80, 35.1p=0.040
Mean difference at 48 h
23.0
95% CI 5.20, 40.8p=0.011
Mean difference at 60 h
28.0
95% CI 9.24, 46.7p=0.004
Mean difference at 72 h
33.0
95% CI 13.0, 53.0p=0.001
Secondary outcomes
Average resting pain score, time to ambulation, same-day discharge, LOS, patient-reported functional outcomes
- No significant differences between treatment arms
Original publication
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