Pediatric anesthesia & critical care

Complications of Pediatric Midline Catheters: A Prospective Observational Pilot Study

Anesth AnalgPublished Prospective observational study

Authors' conclusion

In children, thrombotic and mechanical complications of midline catheters are common, but only few VTEs are severe enough to warrant anticoagulation therapy. Systemic infectious complications are rare.

Study context

Population
Children with midline catheters at a tertiary multidisciplinary pediatric hospital
Participants
100 midline catheters
Outcome
Incidence of catheter-related VTE (Doppler ultrasonography after removal to detect asymptomatic VTE)
Methodological detailspilot, consecutive patients, single-centre
  • Pilot
  • Consecutive patients
  • Single-centre

Main finding

As reported in the abstract

Catheter-related VTE
GroupValueIncidence rate per 1000 catheter days
Midline catheters30% (95% CI 21%–40%)39 (95% CI, 26-55)

Midline catheters

Value30% (95% CI 21%–40%)
Incidence rate per 1000 catheter days39 (95% CI, 26-55)

Observational data: associations, not effects.

Further findings

OutcomeSaphenous veinArm vein
Catheter-related VTE by insertion site (subgroup)
Catheters1486

Catheter dwell time

Median catheter dwell time, days (range as printed)
6 (4-8) days

Catheter-related venous thromboembolism (VTE) by insertion site (subgroup)

Suggests an imbalance in favour of arm vein insertion site

Catheter removal unintentionally or due to complications

Catheters removed unintentionally or due to complications
30 (30%)
Of these, needed additional intravenous (IV) access to complete intended therapy
22

Safety

Anticoagulation therapy for catheter-related VTE

Patients needing anticoagulation therapy due to catheter-related VTE
2

Catheter-related bloodstream infection

No catheter-related bloodstream infection occurred
0 (95% CI, 0%-4%) (95% CI)

Mechanical complications

Midline catheters with mechanical complications
33 (33%; 95% CI, 24%-43%)

Original publication

Complications of Pediatric Midline Catheters: A Prospective Observational Pilot Study. Anesth Analg. Published 12 December 2022. doi:10.1213/ane.0000000000006328

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