Pediatric anesthesia & critical care
Complications of Pediatric Midline Catheters: A Prospective Observational Pilot Study
Authors' conclusion
In children, thrombotic and mechanical complications of midline catheters are common, but only few VTEs are severe enough to warrant anticoagulation therapy. Systemic infectious complications are rare.
Study context
- Population
- Children with midline catheters at a tertiary multidisciplinary pediatric hospital
- Participants
- 100 midline catheters
- Outcome
- Incidence of catheter-related VTE (Doppler ultrasonography after removal to detect asymptomatic VTE)
Methodological detailspilot, consecutive patients, single-centre
- Pilot
- Consecutive patients
- Single-centre
Main finding
As reported in the abstract
Catheter-related VTE
| Group | Value | Incidence rate per 1000 catheter days |
|---|---|---|
| Midline catheters | 30% (95% CI 21%–40%) | 39 (95% CI, 26-55) |
Midline catheters
Value30% (95% CI 21%–40%)
Incidence rate per 1000 catheter days39 (95% CI, 26-55)
Observational data: associations, not effects.
Further findings
| Outcome | Saphenous vein | Arm vein |
|---|---|---|
| Catheter-related VTE by insertion site (subgroup) | ||
| Catheters | 14 | 86 |
Catheter dwell time
- Median catheter dwell time, days (range as printed)
- 6 (4-8) days
Catheter-related venous thromboembolism (VTE) by insertion site (subgroup)
- Suggests an imbalance in favour of arm vein insertion site
Catheter removal unintentionally or due to complications
- Catheters removed unintentionally or due to complications
- 30 (30%)
- Of these, needed additional intravenous (IV) access to complete intended therapy
- 22
Safety
Anticoagulation therapy for catheter-related VTE
- Patients needing anticoagulation therapy due to catheter-related VTE
- 2
Catheter-related bloodstream infection
- No catheter-related bloodstream infection occurred
- 0 (95% CI, 0%-4%) (95% CI)
Mechanical complications
- Midline catheters with mechanical complications
- 33 (33%; 95% CI, 24%-43%)
Original publication
Complications of Pediatric Midline Catheters: A Prospective Observational Pilot Study. Anesth Analg. Published 12 December 2022. doi:10. 1213/ ane. 0000000000006328
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