Paediatric anaesthesia & critical care

Local Adverse Events Associated with Peripheral Vasoactive Infusion in Children: A Systematic Review with Meta-analysis

J Cardiothorac Vasc AnesthPublished Systematic review and meta-analysis

Authors' conclusion

Based on the findings of this meta-analysis, the incidence rate of local adverse events associated with peripheral vasoactive infusion appears to be low.

Study context

Population
Critically ill children receiving vasoactive agents, including epinephrine and norepinephrine, via peripheral venous catheter or intraosseous access12 observational studies, 1 RCT
Comparison
Peripheral venous catheters or intraosseous access vs peripheral venous catheters only vs intraosseous access only
Outcome
Local adverse events associated with peripheral vasoactive infusion:
  • E.g.
  • Extravasation
  • Infiltration
Methodological detailsupdated systematic review
  • Updated systematic review

Pooled result

As reported in the abstract

Pooled incidence of local adverse events

Original publication

Local Adverse Events Associated with Peripheral Vasoactive Infusion in Children: A Systematic Review with Meta-analysis. J Cardiothorac Vasc Anesth. Published 13 August 2024. doi:10.1053/j.jvca.2024.08.020

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