Pediatric anesthesia & critical care
Compression only CPR and mortality in pediatric out-of-hospital cardiac arrest during COVID-19 pandemic
Main finding · 30-day mortalityResult — go to the resultAdjusted relative risk 1.16 95 % CI 1.08–1.24Authors' conclusion
The findings highlight the importance of rescue breathing in pediatric OHCA. CO-CPR, while suitable for adults, may compromise outcomes in children.
Study context
- Population
- Pediatric out-of-hospital cardiac arrest (OHCA) patients (≤17 years) receiving bystander CPR, All-Japan Utstein Registry, January 2017–December 20213,352 received bystander CPR
- Participants
- 7,162 patients
- Exposure
- Compression-only CPR (CO-CPR) vs rescue breathing cardiopulmonary resuscitation (RB-CPR) by bystanders
- Outcome
- Mortality
- Follow-up
- 30 days
Methodological detailsnationwide registry
- Nationwide registry
Main finding
30-day mortality
Adjusted relative risk
1.16
95 % CI 1.08–1.24
CO-CPR vs RB-CPR
aRR 1.16 (95 % CI 1.08–1.24)
As reported in the abstract
Observational data: associations, not effects.
Secondary outcomes
| Outcome | aRR (95 % CI) | |
|---|---|---|
| Unfavorable neurological outcome (CPC 3-5) | 1.10 (1.05–1.16) | |
| 0.512Adjusted relative risk (log scale) |
RB-CPR use, pre-pandemic vs pandemic
Excess deaths attributable to decreased RB-CPR during pandemic
- Estimated excess deaths annually
- 10.7
Subgroups by age and arrest etiology
- Consistent across age groups and arrest etiologies, particularly for non-cardiac causes
Original publication
Compression only CPR and mortality in pediatric out-of-hospital cardiac arrest during COVID-19 pandemic. Resuscitation. Published 4 July 2025. doi:10.
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