Perioperative medicine & outcomes

Consequences of preoperative cardiac stress testing—A cohort study

J Clin AnesthPublished Retrospective cohort study

Authors' conclusion

Preoperative cardiac stress testing likely induces coronary angiography and cardiac interventions while decreasing use of noncardiac surgery and delaying surgery for patients who ultimately proceed to noncardiac surgery. Despite changes to processes of care, our results do not support a causal relationship between stress testing and postoperative mortality.

Study context

Population
Patients visiting a dedicated preoperative risk assessment and optimization clinic before noncardiac nonophthalmologic surgery, 2008–2018
Participants
118,552 patients · 159,795 visits
Exposure
Preoperative functional cardiac stress testing vs no stress testing
Outcome
Downstream care after stress testing
Methodological detailscausal inference models, integrated health system
  • Causal inference models
  • Integrated health system

Main finding

As reported in the abstract

Stress testing vs No stress testingRelative risk (95% CI)
Coronary angiography
8.6(6.1–12.1)
Percutaneous coronary intervention
4.1(1.8–9.2)
Cardiac surgery
6.8(4.9–9.4)
Noncardiac surgery
0.77(0.75–0.79)
Delay to noncardiac surgery, patients completing noncardiac surgery
mean delay 28.3 days (95% CI 23.1–33.6)

Observational data: associations, not effects.

Further findings

Mortality (time-to-mortality and 1-year mortality)

Higher mortality with stress testing in unadjusted analysis; no association in causal inference analyses

Original publication

Consequences of preoperative cardiac stress testing—A cohort study. J Clin Anesth. Published 5 July 2023. doi:10.1016/j.jclinane.2023.111158

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