Perioperative medicine & outcomes

Pathological findings associated with the updated European Society of Cardiology 2022 guidelines for preoperative cardiac testing: an observational cohort modelling study

Br J AnaesthPublished Secondary analysis of the MET-REPAIR prospective observational cohort study

Authors' conclusion

The 2022 update for preoperative cardiac testing resulted in a relevant increase in tests receiving a stronger recommendation. The updated recommendations for TTE did not improve the yield of pathological cardiac testing.

Study context

Population
Patients undergoing preoperative cardiac evaluation in the international MET-REPAIR cohort39% female
Participants
15,529 patients
Comparison
ESC 2022 vs 2014 guideline recommendations for preoperative cardiac testing (TTE, stress imaging)
Primary endpoint
Reduced ejection fraction (EF<40%), stress-induced ischaemia, and MACE
Methodological detailsinternational, second-order Monte Carlo simulations, multivariable regression
  • International
  • Second-order Monte Carlo simulations
  • Multivariable regression

Primary result

As reported in the abstract

2022 update changed recommendation for preoperative TTE

39.7%

2022 update changed recommendation for preoperative stress imaging

12.9%

Missed EF <40% per fewer conducted TTE

1 every 3

Additional stress imaging per additionally detected ischaemia event

4 per 1

Further findings

NT-proBNP use for risk estimation

Did not improve the yield of pathological findings

Original publication

Pathological findings associated with the updated European Society of Cardiology 2022 guidelines for preoperative cardiac testing: an observational cohort modelling study. Br J Anaesth. Published 9 February 2024. doi:10.1016/j.bja.2023.12.036

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