Perioperative medicine & outcomes
Risk assessment for major adverse cardiovascular events after noncardiac surgery using self-reported functional capacity: international prospective cohort study
Authors' conclusion
Assessment of self-reported functional capacity expressed in METs or using the other measures assessed here did not improve prognostic accuracy compared with clinical risk factors.
Study context
- Population
- Patients undergoing elective noncardiac surgery at elevated cardiovascular risk (June 2017 to April 2020)loss of follow-up 2%
- Participants
- 15,406 patients
- Exposure
- Clinical risk model with vs without self-reported functional capacity measures for MACE prediction
- Outcome
- In-hospital MACE:
- CV mortality
- Non-fatal cardiac arrest
- Acute MI
- Stroke
- HF requiring transfer to higher care
- Prolonging ICU/intermediate care stay ≥24 h
- Follow-up
- In-hospital
Methodological detailsinternational
- International
Main finding
As reported in the abstract
Discrimination for MACE (ROC AUC)
Baseline
0.74
CI 0.71–0.77
Baseline+metabolic equivalents (METs)
0.74
CI 0.71–0.77
Baseline+floors climbed
0.75
CI 0.71–0.78
Baseline+fitness vs peers
0.74
CI 0.71–0.77
Baseline+physical activity
0.75
CI 0.72–0.78
Observational data: associations, not effects.
Further findings
In-hospital MACE incidence
- Patients with MACE
- 274 (1.8%)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Risk assessment for major adverse cardiovascular events after noncardiac surgery using self-reported functional capacity: international prospective cohort study. Br J Anaesth. Published 1 April 2023. doi:10.
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