Continuity with caveats in anesthesia: state and response entropy of the EEG
Authors' conclusion
SE and RE index values do not adhere to a continuous distribution, instead displaying prominent pillar indices with a consistent pattern of occurrence across all age groups.
Study context
- Population
- Patients who underwent GA with processed intraoperative EEG (GE Entropy Module SE, Response Entropy (RE), Burst Suppression Ratio (BSR))
- Participants
- 15,608 patients
- Outcome
- Distribution of SE and RE index values
Methodological detailssingle-centre, Histograms, heat maps and fitted custom non-Gaussian curves; distributions compared by Kolmogorov-Smirnov test and Kullback-Leibler divergence
- Single-centre
- Histograms, heat maps and fitted custom non-Gaussian curves; distributions compared by Kolmogorov-Smirnov test and Kullback-Leibler divergence
Main finding
As reported in the abstract
- Distinct pillar indices for both SE and RE (index values with higher probability of occurrence than others)
- Pillar index values not age-dependent; non-equidistant distribution pattern
- Phenomenon occurs independently of the BSR distribution
Observational data: associations, not effects.
Original publication
Continuity with caveats in anesthesia: state and response entropy of the EEG. J Clin Monit Comput. Published 3 April 2024. doi:10. 1007/ s10877-024-01130-9
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