Continuous Bilateral Lower-Limb Near-Infrared Spectroscopy Monitoring in Patients on Intra-aortic Balloon Pump Support: A Prospective Feasibility and Physiology Study
Authors' conclusion
Continuous bilateral lower-limb rSO₂ monitoring is feasible throughout IABP support and produces a physiologically coherent signal that correlates moderately with objective NVA parameters and is lower in patients who do not survive to discharge.
Study context
- Population
- Consecutive adults on intra-aortic balloon pump (IABP) support via femoral arterial access, cardiac care unit of a tertiary cardiac center, Singapore
- Participants
- 50 consecutive adults
- Exposure
- Nonsurvivors vs survivors
- Outcome
- Minimum contralateral (left) rSO₂
Methodological detailssingle-centre, feasibility and physiology study
- Single-centre
- Feasibility and physiology study
Main finding
As reported in the abstract
P = 0.024
- Ipsilateral (right) side: directionally similar but nonsignificant trend
- P = 0.083
Observational data: associations, not effects.
Further findings
Low rSO₂ (<40%) in either limb and mortality
| OR (95% CI) | P value | ||
|---|---|---|---|
| Low rSO₂ (<40%) | 3.16 (0.55–18.11) | P = 0.197 | |
| 0.050.21520Odds ratio (log scale) |
Predictors of mortality
| OR | |
|---|---|
| SepsisStatistically significant · only statistically significant predictors | 13.0 |
| RRTStatistically significant · only statistically significant predictors | 7.1 |
Correlation of rSO₂ with neurovascular assessment (NVA) parameters (bilaterally)
- Capillary refill time (Spearman rs)
- ≈ 0.50
- Pulse quality (Spearman rs)
- ≈ 0.38
- No correlation with temperature change, which deteriorated in >92% of limbs
Right femoral access
- Right femoral access (47 of 50)
- 94%
Safety
- No patient developed acute limb ischemia
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Continuous Bilateral Lower-Limb Near-Infrared Spectroscopy Monitoring in Patients on Intra-aortic Balloon Pump Support: A Prospective Feasibility and Physiology Study. J Cardiothorac Vasc Anesth. Published 21 September 2026. doi:10.
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