Perioperative medicine & outcomes
Continuous glucose monitoring for diabetes mellitus in the perioperative and intensive care setting: a prospective observational validation study✰
Authors' conclusion
For the vast majority of interstitial glucose measurements, CGM was accurate in people with diabetes mellitus. Although overall performance was good, caution may be warranted when interpreting CGM data during periods of impaired peripheral perfusion.
Study context
- Population
- People with diabetes mellitus requiring glucose-lowering medication undergoing surgery or admission to the ICUparticipants, 1212 paired point-of-care (POC) and continuous glucose monitoring (CGM) measurements
- Participants
- 58 people
- Exposure
- Accuracy of CGM compared with POC monitors
- Outcome
- Agreement between CGM and POC measurements, defined as median absolute relative difference (MARD)
Methodological detailsvalidation study
- Validation study
Main finding
As reported in the abstract
Median median absolute relative difference (MARD)
10.9%
5.1–19.4%
Observational data: associations, not effects.
Further findings
| Outcome | Mean difference (mM) (95% limits of agreement CI) | |
|---|---|---|
| Bland-Altman analysisSimilar CGM and POC measurements | −1 (−5.6 to 3.4) | |
| −10−505Difference, mM (linear scale) |
Clinically acceptable ranges (clarke error grid (CEG) zones A and B)
- Paired POC and CGM measurements within CEG zones A and B
- 1186 of 1212 (98%)
MARD during periods of hypoperfusion (secondary analysis)
- MARD higher during periods of hypoperfusion
- 4.5% (95% confidence interval 2.3-6.7%)
- Hypoperfusion defined as a mean arterial pressure of <65 mm Hg, infusions with vasopressors, or reduced peripheral perfusion index
Hypoglycaemia (<4 mM)
- Hypoglycaemia did not occur; no paired readings were obtained
Original publication
Continuous glucose monitoring for diabetes mellitus in the perioperative and intensive care setting: a prospective observational validation study✰. Br J Anaesth. Published 12 October 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →