ICU sedation, delirium & recovery
Critically ill patient mortality by age: long-term follow-up (CIMbA-LT)
Authors' conclusion
Critically ill patients' mortality peaked in the first 30 days after ICU admission. Older critically ill patients had higher all-cause mortality, including a higher hospital SMR. A long-term increased relative mortality risk was noted in patients discharged alive from the hospital, but this was more noticeable in younger patients.
Study context
- Population
- Patients admitted to Portuguese multipurpose intensive care unit (ICUs) over 4 years, followed for two years after ICU admission15.8% over 80 years
- Participants
- 37.118 patients
- Exposure
- Mortality by age group
- Outcome
- Short- and long-term all-cause mortality (SMR by SAPS II; follow-up risk vs national demographic data)
- Follow-up
- Two years
Methodological detailsmulticentric, nationwide, observational, Mean Simplified Acute Physiology Score (SAPS) II 42.8 ± 19.4
- Multicentric
- Nationwide
- Observational
- Mean SAPS II 42.8 ± 19.4
Main finding
As reported in the abstract
Mortality, all patients
- ICU all-cause mortality
- 16.1%
- Survival to hospital discharge
- 76%
- SMR at hospital discharge (SAPS II overestimated hospital mortality), 95% CI 0.63-0.76
- 0.7
- 1-year SMR (accurately predicted), 95% CI 0.98-1.08
- 1.01
- 1-year relative mortality risk in patients discharged alive, 95% CI 5.8-6.7
- 6.3
Observational data: associations, not effects.
Further findings
Relative mortality risk
| Outcome | Older | Younger |
|---|---|---|
| 1-year relative mortality risk in patients discharged alive from hospital (vs national demographic data), by age | 2.4 (95% CI 2.2–2.7) | 21.1 (95% CI 15.1–39.6) |
- 1-year relative mortality risk in patients discharged alive from hospital (vs national demographic data), by age — 1-year relative mortality risk, all patients discharged alive
- 6.3
- 1-year relative mortality risk in patients discharged alive from hospital (vs national demographic data), by age: all patients: 95% CI 5.8-6.7
Hospital SMR by age · hospital discharge
- Older patients had higher short- and long-term mortality and slightly higher hospital SMR
- 0.76 vs. 0.69
Original publication
Critically ill patient mortality by age: long-term follow-up (CIMbA-LT). Ann Intensive Care. Published 11 February 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →