Cryoneurolysis Thermal Graphs: In Vivo Descriptive Data from Ultrasound-guided Percutaneous Thermocouples
Authors' conclusion
During percutaneous cryoneurolysis, the temperature of tissue is frequently deceptively warm relative to the returning gas and tissue frequently does not reach an adequately cold temperature; prolonging gas treatment from 3 to 5 min improves the success of reaching therapeutic temperatures; the presence of a peripheral nerve block appears to lessen the chance of reaching therapeutic temperatures
Study context
- Population
- Patients undergoing mastectomy or treated for traumatic rib fractures, receiving ultrasound-guided cryoneurolysis of multiple intercostal nerves with a percutaneous thermocouple ≈3 mm from the cryoprobe shaft31 nerves
- Participants
- 3 vs 3
- Comparison
- Mastectomy vs Rib fractures
- Mastectomyn = 3
- Rib fracturesn = 3reference
- Outcome
- Tissue temperature adjacent to cryoprobe vs returning argon gas
Methodological detailsconvenience sample, in vivo, no statistical analysis
- Convenience sample
- In vivo
- No statistical analysis
Main finding
As reported in the abstract
Adjacent tissue did not reach −20°C after 3 min (% of treatments)
71%
n = 5
Adjacent tissue did not reach −20°C after 5 min (% of treatments)
42%
n = 10
Coldest mean tissue temperature warmer than returning gas, without nerve block
60°C
Coldest mean tissue temperature warmer than returning gas, with concurrent nerve block
95°C
Original publication
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