Decreasing the pressure of endotracheal tube cuff slowly with a constant speed can decrease coughing incidence during extubation: a randomized clinical trial
Authors' conclusion
Decreasing the pressure of endotracheal tube cuff slowly with a constant speed can significantly reduce the incidence of coughing during extubating period, stabilize hemodynamics, and reduce the incidence of adverse reactions.
Study context
- Population
- Patients undergoing elective noncardiac surgery under GA with endotracheal intubation
- Participants
- 90 patients
- Comparison
- P vs C
- Primary endpoint
- Incidence of coughing during extubation period
Primary result
As reported in the abstract
Incidence of coughing during extubation
- Coughing incidence significantly decreased in P vs C
- Coughing initiated immediately at time of balloon deflation
- P vs C: P = 0.001
Further findings
| Outcome | P value |
|---|---|
| MAP and HR · MAP T2-T4; HR T2-T5 | P < 0.05 for all |
- Mean arterial pressure (MAP) and HR: MAP significantly decreased at T2-T4 and HR at T2-T5 in group P
Safety
| Outcome | P value |
|---|---|
| Pharyngolaryngeal discomfort after extubationSignificantly reduced in group P | P = 0.021 |
Original publication
Decreasing the pressure of endotracheal tube cuff slowly with a constant speed can decrease coughing incidence during extubation: a randomized clinical trial. Perioper Med (Lond). Published 30 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →