Paediatric anaesthesia & critical care
Automated Versus Manual Endotracheal Tube Cuff Pressure Control in Mechanically Ventilated Children: A Randomized Crossover Trial
Authors' conclusion
Automated cuff pressure control more reliably maintains target pressure and minimizes clinically important deviations compared to manual management.
Study context
- Population
- Mechanically ventilated pediatric patients (1 month-18 years) expected to require ventilation for ≥ 48 h768 measurements
- Participants
- Thirty-two participants
- Comparison
- Automated vs manual endotracheal tube cuff pressure control
- Primary endpoint
- Frequency and cumulative duration of off-target cuff pressure exposure
Methodological detailsprospective
- Prospective
Primary result
As reported in the abstract
Off-target cuff pressure
Off-target cuff pressure
High-pressure episodes (> 25 cmH2O)
P < 0.001
Total time outside target range Automated 10 h · Manual 118 h · P < 0.001
- Manual vs Automated: P < 0.001 — low cuff pressure episodes (< 15 cmH2O)
Secondary outcomes
Nursing workload · significantly lower in the automated phase
P < 0.001
Original publication
Automated Versus Manual Endotracheal Tube Cuff Pressure Control in Mechanically Ventilated Children: A Randomized Crossover Trial. Paediatr Anaesth. Published 16 July 2026. doi:10. 1002/ pan. 70268
Composed by AI from the published abstract and checked against it. How Briefs are made →