ICU sedation, delirium & recovery

Delirium and Self-Reported Driving Behaviors and Outcomes After Critical Illness

JAMA Netw OpenPublished Longitudinal cohort study

Main finding · Self-rated driving skill (Driver Skill Inventory) per delirium durationResult — go to the resultRegression coefficient −0.10 95% CI −1.13 to 0.93

Authors' conclusion

In this cohort study of survivors of critical illness, ICU delirium was not independently associated with long-term changes in driving behaviors after critical illness; survivors of critical illness self-reported significant decreases in transportation independence and driving skill after hospital discharge, independent of delirium duration during hospitalization.

Study context

Population
Survivors of critical illness residing within 200 miles of Nashville, Tennessee, surveyed 2 to 6 years after critical illnessof 333 survivors
Participants
151 survivors
Exposure
Association of intensive care unit (ICU) delirium duration with long-term driving behaviors
Outcome
Self-rated driving skill (Driver Skill Inventory)
Methodological detailsmulticentre, Survey at median (range) 3.7 (2.1-6.2) years after critical illness; median (IQR) delirium duration 1 (0-4) day
  • Multicentre
  • Survey at median (range) 3.7 (2.1-6.2) years after critical illness; median (IQR) delirium duration 1 (0-4) day

Main finding

As reported in the abstract

Self-rated driving skill (Driver Skill Inventory) per delirium duration

Regression coefficient

−0.10

95% CI −1.13 to 0.93

Observational data: associations, not effects.

Secondary outcomes

Risky driving behaviour (Mini Driver Behavior Questionnaire), association with delirium duration

Regression coefficient per delirium duration, not independently associated
−0.46 (95% CI, −1.97 to 1.06)

Driving distance after vs before critical illness

After critical illness, median (IQR) miles per week
60 (25-150)
Prehospitalization estimate, median (IQR) miles per week
105 (58-250)
Significantly lower after critical illness
P < 0.001

Driving skill on return to driving

Driving skill, median (IQR) on a 48-point scale, significantly lower on return to driving
34 (26-38); P < .001

Safety orientation on return to driving

Safety orientation, median (IQR) on a 48-point scale, significantly lower on return to driving
38 (35-46); P < .001

Time to driving resumption after ICU discharge

Driving resumption, median (IQR) months after ICU discharge
1.9 (0.8-6.0)

Adults ≥65 years (subgroup)

Decrements in driving skill and safety orientation persisted

Original publication

Delirium and Self-Reported Driving Behaviors and Outcomes After Critical Illness. JAMA Netw Open. Published 2 September 2025. doi:10.1001/jamanetworkopen.2025.31224

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