Safety, quality & education

Dependability of Large Language Models in Cardiovascular Medicine: A Scoping Review

J Cardiothorac Vasc AnesthPublished Scoping review

Authors' conclusion

Although some LLM-generated responses to cardiovascular-related questions exhibit acceptable levels of quality, significant drawbacks persist. These include verbosity, inaccuracies, occasional misinformation, inconsistent outputs to identical questions, bias, and poor reproducibility.

Study context

Population
Studies on development, implementation and assessment of large language models (LLMs) in cardiovascular medicine, published August 2020–February 2025
Participants
25 publications
Outcome
Performance of LLMs in responding to cardiology-related questions
Methodological detailsCochrane methodology, PRISMA guidelines, 3 databases (PubMed, Web of Science, Embase)
  • Cochrane methodology
  • PRISMA guidelines
  • 3 databases (PubMed, Web of Science, Embase)

Main finding

As reported in the abstract

  • Assessment methodology varied considerably across studies
  • LLMs showed potential utility in cardiovascular decision-making, myocarditis management, cardiac arrest diagnosis and treatment, and image differentiation

Original publication

Dependability of Large Language Models in Cardiovascular Medicine: A Scoping Review. J Cardiothorac Vasc Anesth. Published 22 July 2025. doi:10.1053/j.jvca.2025.07.026

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