Pediatric anesthesia & critical care
Description of the Properties of an Herbal Admixture (BabySed) During Trans‐Thoracic Echocardiography in Children Under Six Years Old, and Comparison to Chloral Hydrate
Primary result · Ramsay sedation score ≥ 4Result — go to the resultOdds ratio 0.31 95% CI 0.03–3.16Authors' conclusion
The results of our study suggest that an herbal mixture can be effectively used for procedural sedation during echocardiography in children.
Study context
- Population
- Children under six years old undergoing trans-thoracic echocardiography
- Participants
- 70 participants
- Comparison
- Herbal mixture vs chloral hydrate for sedation
- Primary endpoint
- Adequate sedation (Ramsay sedation score ≥ 4)
Methodological detailsConducted April 2022 to July 2022
- Conducted April 2022 to July 2022
Primary result
Ramsay sedation score ≥ 4
Odds ratio
0.31
95% CI 0.03–3.16
p:0.32
By group
Herbal mixture vs Chloral hydrate
OR 0.31 (95% CI 0.03–3.16); p:0.32
As reported in the abstract
Further findings
- Shorter onset of action with chloral hydrate
- P = 0.029
- Longer duration of action with chloral hydrate
- P < 0.001
Safety
- Higher adverse effects with chloral hydrate
- P < 0.001
- No oxygen desaturation or BP fluctuations during procedure or recovery
Original publication
Description of the Properties of an Herbal Admixture (BabySed) During Trans‐Thoracic Echocardiography in Children Under Six Years Old, and Comparison to Chloral Hydrate. Paediatr Anaesth. Published 4 August 2025. doi:10. 1111/ pan. 70030
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