Pediatric anesthesia & critical care
Using capnography in children to prevent oxygen desaturation during procedural sedation: A randomised trial
Primary resultResult — go to the resultOdds ratio 0.38 95% CI 0.19–0.75Authors' conclusion
Capnography significantly reduced the incidence of oxygen desaturation in paediatric patients undergoing procedural sedation outside the operating room.
Study context
- Population
- Children undergoing sedation outside the operating room (oral chloral hydrate, IV midazolam, ketamine or a combination), tertiary children's hospital197 analysed
- Participants
- 214 children
- Comparison
- Pulse oximetry plus capnography vs pulse oximetry alone
- Capnographyn = 96
- Controln = 101reference
- Primary endpoint
- Incidence of oxygen desaturation (decrease ≥5% from baseline oxygen saturation)
Methodological detailsage-stratified, without blinding, single-centre
- Age-stratified
- Without blinding
- Single-centre
Primary result
As reported in the abstract
Odds ratio
0.38
95% CI 0.19–0.75
P = 0.005
Events by treatment group
Capnography vs Control
OR 0.38 (95% CI 0.19–0.75); P = 0.005
Further findings
Oxygen saturation at intervention initiation · higher in the capnography group
P = 0.003
Severe oxygen desaturation (<90% or <85%)
- Did not differ between the two groups
Original publication
Using capnography in children to prevent oxygen desaturation during procedural sedation: A randomised trial. Eur J Anaesthesiol. Published 11 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →