Cardiac arrest & resuscitation

Determinants of survival in sudden cardiac arrest manifesting with pulseless electrical activity

ResuscitationPublished Prospective cohort study

Authors' conclusion

Key determinants for survival from PEA-SCA were young age, witnessed status, public location and pre-existing COPD/asthma. Survival outcomes in witnessed PEA cases were better than expected, even with delayed EMS response.

Study context

Population
Out-of-hospital sudden cardiac arrests (SCA) with pulseless electrical activity (PEA) as presenting rhythm and emergency medical services (EMS)-attempted resuscitation; Portland, OR metro area (2002–2017) and Ventura County, CA (2015–2021)
Participants
1,704 PEA-SCA cases
Exposure
PEA-SCA survivors vs non-survivors
  • Survivorsn = 173
  • Non-survivorsn = 1,531reference
Outcome
Predictors of survival from PEA-SCA
Methodological detailscommunity-based, 2 ongoing prospective studies (Oregon SUDS, Ventura PRESTO)
  • Community-based
  • 2 ongoing prospective studies (Oregon SUDS, Ventura PRESTO)

Main finding

As reported in the abstract

Survival from PEA-SCA
Overall survival
10.2%
Survival, healthcare unit location
16.9%
Survival, public location
18.1%
Survival, home
9.3%
Survival, care facility
5.7%

Observational data: associations, not effects.

Further findings

Survival in witnessed cases with EMS response time >10 minutes

Survival rate
10%

Original publication

Determinants of survival in sudden cardiac arrest manifesting with pulseless electrical activity. Resuscitation. Published 18 April 2023. doi:10.1016/j.resuscitation.2023.109798

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