Cardiac arrest & resuscitation
Survival for Nonshockable Cardiac Arrests Treated With Noninvasive Circulatory Adjuncts and Head/Thorax Elevation*
Main finding · Survival to hospital discharge (unadjusted)Result — go to the resultOR for survival to hospital discharge 2.46 95% CI 1.55–3.92Authors' conclusion
These findings indicate that, compared with C-CPR, there are strong associations between rapid AHUP-CPR treatment and greater likelihood of patient survival, as well as survival with good neurological function, in cases of nonshockable OHCA.
Study context
- Population
- Adults with nontraumatic out-of-hospital cardiac arrest (OHCA) with nonshockable presentations (asystole/pulseless electrical activity), North American 9–1–1 emergency medical services (EMS) agencies353 per group matched
- Participants
- 380 vs 1,852
- Exposure
- AHUP-CPR vs conventional CPR (C-CPR)
- AHUP-CPRn = 380
- C-CPRn = 1,852reference
- Outcome
- Survival to hospital discharge
Methodological detailspropensity score matching, matching of time to EMS-initiated cardiopulmonary resuscitation (CPR), historical trial controls
- Propensity score matching
- Matching of time to EMS-initiated CPR
- Historical trial controls
Main finding
Survival to hospital discharge (unadjusted)
OR for survival to hospital discharge
2.46
95% CI 1.55–3.92
Events by group
AHUP-CPR vs C-CPR
OR for survival to hospital discharge 2.46 (95% CI 1.55–3.92)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | AHUP-CPR | C-CPR | OR for survival to hospital discharge (95% CI) | |
|---|---|---|---|---|
| Survival to hospital discharge (propensity score matched) | 7.6% | 2.8% | 2.84 (1.35–5.96) | |
| 0.20.5125OR for survival to hospital discharge (log scale) |
- Survival to hospital discharge (propensity score matched): propensity score matched (353 per group)
Survival and neurologically favorable survival by speed of AHUP-CPR application
- Faster AHUP-CPR application markedly amplified odds of survival and neurologically favorable survival
Original publication
Survival for Nonshockable Cardiac Arrests Treated With Noninvasive Circulatory Adjuncts and Head/Thorax Elevation*. Crit Care Med. Published 19 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →