Development and validation of the tic score for early detection of traumatic coagulopathy upon hospital admission: a cohort study
Authors' conclusion
The TIC Score is quick and easy to calculate and can accurately identify patients with TIC upon hospital admission.
Study context
- Population
- Critically injured patients at hospital admission, three level-1 trauma centers3 sets
- Participants
- 3,489 participants
- Outcome
- Score performance for prediction of TIC (PTratio > 1.2 at hospital admission)
- Follow-up
- Hospital admission
Methodological detailsscore development and validation, retrospective and prospective validation sets, multicentre
- Score development and validation
- Retrospective and prospective validation sets
- Multicentre
Performance
As reported in the abstract
Identification of TIC
| Test or model | AUC | NPV (score < 2, rule-out) | PPV (score ≥ 6, rule-in) |
|---|---|---|---|
| Trauma-induced coagulopathy (TIC) Score | 0.82 (95% CI 0.81-0.84) | 93% | 92% |
Trauma-induced coagulopathy (TIC) Score
AUC0.82 (95% CI 0.81-0.84)
NPV (score < 2, rule-out)93%
PPV (score ≥ 6, rule-in)92%
Further findings
TIC prevalence · hospital admission
- TIC observed
- 22% (95% CI 21-24%)
Original publication
Development and validation of the tic score for early detection of traumatic coagulopathy upon hospital admission: a cohort study. Crit Care. Published 18 May 2024. doi:10.
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