Trauma‐induced coagulopathy across age pediatric groups: A retrospective cohort study evaluating testing and frequency
Authors' conclusion
Contrary to previous reports and using age-specific TIC criteria, younger children are not at lower risk of TIC than older children when controlling for injury severity.
Study context
- Population
- Injured children and adolescents at a large Level I trauma center, 2015–2020333 isolated severe traumatic brain injury (TBI)
- Participants
- 2,409 children
- Exposure
- Coagulation testing and trauma-induced coagulopathy (TIC) frequency across pediatric age groups
- Outcome
- Coagulation testing patterns and frequency of TIC (age-specific reference ranges, controlling for injury severity)
- Follow-up
- Presentation and first 72 h
Methodological detailssingle-centre, Level I trauma center
- Single-centre
- Level I trauma center
Main finding
As reported in the abstract
TIC frequency and testing by age group
TIC at presentation
22%
TIC by 72 h
35%
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| In-hospital mortality with TICTIC vs No TIC | 4.10 (2.06–8.17) | |
| 0.10.31310Odds ratio (log scale) |
TIC frequency, isolated severe TBI (subgroup)
- No difference in TIC frequency between age groups
Original publication
Trauma‐induced coagulopathy across age pediatric groups: A retrospective cohort study evaluating testing and frequency. Paediatr Anaesth. Published 22 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →