Cardiac arrest & resuscitation
Development of the epidemiology and outcomes of out-of-hospital cardiac arrest using data from the German Resuscitation Register over a 15-year period (EpiCPR study)
Authors' conclusion
Despite a significant increase in bystander and telephone CPR rates, no improvement in 30-day survival and hospital discharge rate with CPC1,2 was observed.
Study context
- Population
- Out-of-hospital Cardiac Arrest (OHCA) patients in the German Resuscitation Register
- Participants
- 42,997 patients
- Exposure
- 2006-2010 vs 2011-2015 vs 2016-2020
- 2006-2010n = 3,471reference
- 2011-2015n = 16,122
- 2016-2020n = 23,404
- Outcome
- 30-day survival and hospital discharge with good neurological outcome (CPC 1,2)
Methodological detailsGerman Resuscitation Register, matched-pair analysis, multivariate logistic regression
- German Resuscitation Register
- Matched-pair analysis
- Multivariate logistic regression
Main finding
As reported in the abstract
30-day survival and hospital discharge with CPC 1/2
- Matched pairs: higher CPC 1,2 rate (8.8 vs 10.2%)
- p < 0.03
Observational data: associations, not effects.
Further findings
Epidemiological and resuscitation-associated trends
- Proportion >80 years, intraosseous (IO) access, supraglottic airway devices, bystander CPR and telephone CPR increased over the study period
Factors associated with outcome (logistic regression)
- IO and SAD had an unfavourable impact on outcome
Original publication
Development of the epidemiology and outcomes of out-of-hospital cardiac arrest using data from the German Resuscitation Register over a 15-year period (EpiCPR study). Resuscitation. Published 21 November 2022. doi:10. 1016/ j. resuscitation. 2022. 11. 014
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