Diagnostic accuracy of ancillary tests for death by neurologic criteria: a systematic review and meta-analysis
Authors' conclusion
Studies assessing ancillary test diagnostic accuracy have an unclear or high risk of bias.
Study context
- Population
- Patients with clinically diagnosed or clinically suspected death by neurologic criteria (determination by neurologic criteria (DNC)) who underwent ancillary testing; pediatric-only studies excluded137 records
- Comparison
- Ancillary tests for DNC vs reference standards
- Outcome
- Pooled sensitivity, clinically diagnosed DNC (n = 8,891)
Methodological detailshierarchical Bayesian models with diffuse priors, QUADAS-2 risk of bias assessment
- Hierarchical Bayesian models with diffuse priors
- QUADAS-2 risk of bias assessment
Pooled result
As reported in the abstract
| Group | Sensitivity (range) |
|---|---|
| Ancillary tests | 0.82-0.93 |
Ancillary tests
Sensitivity (range)0.82-0.93
Further pooled results
| Outcome | Values |
|---|---|
| Pooled sensitivity and specificity, clinically suspected DNC (n = 2,732) | Ancillary tests sensitivity (range) 0.81 and 1.00 · specificity (range) 0.87 and 1.00 |
Risk of bias (QUADAS-2)
- Studies with low risk of bias in all QUADAS-2 domains
- 1 (0.7%)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Diagnostic accuracy of ancillary tests for death by neurologic criteria: a systematic review and meta-analysis. Can J Anaesth. Published 8 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →