Differences in clinical characteristics and quantitative lung CT features between vaccinated and not vaccinated hospitalized COVID-19 patients in Italy
Authors' conclusion
Hospitalized vaccinated patients with COVID-19, although older and with more comorbidities, presented a similar impairment in gas exchange and lung CT scan compared to non-vaccinated patients, but were at a lower risk of mortality.
Study context
- Population
- Consecutive hospitalised COVID-19 patients in Italy admitted January–December 2021
- Participants
- 684 consecutive patients
- Exposure
- Vaccinated vs non-vaccinated hospitalised COVID-19 patients
- Vaccinatedn = 580
- Non-vaccinatedn = 104reference
- Outcome
- Hospital mortality
Methodological detailsconsecutive patients, quantitative lung CT
- Consecutive patients
- Quantitative lung CT
Main finding
As reported in the abstract
Adjusted hazard ratio
0.60
95% CI 0.38–0.95
By group
Vaccinated vs Non-vaccinated
HRadj 0.60 (95% CI 0.38–0.95)
Observational data: associations, not effects.
Further findings
Age
PaO2/FiO2
Respiratory rate
Total lung weight
Lung gas volume
Non-aerated tissue fraction
Age
- Vaccinated significantly older and with more comorbidities
PaO2/FiO2
- Similar
Total lung weight
- Similar
Lung gas volume
- Similar
Non-aerated tissue fraction
- Similar
Original publication
Differences in clinical characteristics and quantitative lung CT features between vaccinated and not vaccinated hospitalized COVID-19 patients in Italy. Ann Intensive Care. Published 3 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →