Perioperative medicine & outcomes
Distinct patterns of intraoperative hemodynamic behavior and postoperative outcomes after major abdominal surgery
Authors' conclusion
Distinct intraoperative hemodynamic phenotypes are associated with graded increases in postoperative complications after major abdominal surgery.
Study context
- Population
- Adults undergoing elective major abdominal surgery with continuous invasive arterial pressure monitoring, single tertiary academic centre (INSPIRE database)
- Participants
- 13,143 adults
- Exposure
- Intraoperative hemodynamic phenotypes 2, 3 and 4 vs phenotype 1
- Outcome
- Postoperative outcomes by hemodynamic phenotype
Methodological detailssingle-centre, unsupervised k-means clustering
- Single-centre
- Unsupervised k-means clustering
Main finding
As reported in the abstract
| Outcome | Phenotype 1 | Phenotype 4 |
|---|---|---|
| AKI | 4.9% | 41.4% |
| ICU admission | 8.3% | 93.2% |
| In-hospital mortality | 0.7% | 6.0% |
- Phenotypes 2 and 3 combined, share of procedures
- 35.0%
Observational data: associations, not effects.
Original publication
Distinct patterns of intraoperative hemodynamic behavior and postoperative outcomes after major abdominal surgery. J Clin Anesth. Published 9 April 2026. doi:10.
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