Pediatric anesthesia & critical care
Dynamics of Oxygen Reserve Index and Arterial Oxygen Partial Pressure in Children: A Prospective Observational Study
Authors' conclusion
ORI consistently correlates with PaO2 in children undergoing cardiac surgery, is unaffected by Hb or EF, and may serve as a useful tool for monitoring oxygenation trends.
Study context
- Population
- Children <7 years undergoing cardiac surgery for congenital heart defects487 data samples analysed
- Participants
- 98 children
- Outcome
- Relationship between ORI and PaO2 (at FiO2 0.21, 0.5, 0.8, before and after CPB)
Main finding
As reported in the abstract
ORI–PaO2 relationship
Nonlinear relationship; PaO2 threshold dividing two ranges (mmHg)
245
Pearson r, PaO2 ≤ 245 mmHg (p < 0.001)
0.516
Pearson r, PaO2 > 245 mmHg (p = 0.035)
0.151
Observational data: associations, not effects.
Further findings
Influencing factors (hemoglobin (Hb), ejection fraction (EF), perfusion index (PI))
- Hb and EF showed no impact; only PI had a mildly negative relationship with Oxygen Reserve Index (ORI) before cardiopulmonary bypass (CPB)
ORI–PaO2 relationship, pre- vs post-CPB
- r2 pre-CPB
- 0.304
- r2 post-CPB
- 0.337
- Relationship remained consistent across both periods
Original publication
Dynamics of Oxygen Reserve Index and Arterial Oxygen Partial Pressure in Children: A Prospective Observational Study. Paediatr Anaesth. Published 21 July 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →