Hemodynamics, fluids & transfusion
Early anaemia and prognosis after knee arthroplasty in nonagenarians admitted to ICU post surgery: a multicentre binational cohort study
Authors' conclusion
In nonagenarians undergoing TKA, anaemia at ICU admission was highly prevalent and associated with increased illness severity, resource utilisation, and elevated long-term mortality.
Study context
- Population
- Patients ≥ 90 years admitted to ICU after total knee arthroplasty (TKA), 2010–2024, haemoglobin (Hb) measured within 24 h, and New Zealand Intensive Care Society (ANZICS) Adult Patient Database
- Participants
- 493 patients
- Exposure
- Mild and moderate/severe anaemia vs non-anaemia at ICU admission
- Outcome
- All-cause mortality, short-term (< 365 days) and long-term (≥ 365 days)
Methodological detailsbinational, multicentre, registry (ANZICS Adult Patient Database)
- Binational
- Multicentre
- Registry (ANZICS Adult Patient Database)
Main finding
As reported in the abstract
All-cause mortality
Hazard ratio (95% CI)P value
Mild vs Non-anaemia
2.08(1.05–4.13)
P = 0.036Severe anaemia
1.98(1.05–3.73)
P = 0.035Observational data: associations, not effects.
Secondary outcomes
Illness severity (APACHE III)
- Severe anaemia associated with higher illness severity, median APACHE III (p = 0.013)
- 57 vs 54
ICU length of stay (LOS)
- Severe anaemia associated with prolonged ICU stay (p = 0.008)
- 18% longer
Hospital LOS
- Severe anaemia associated with longer hospitalisation (p = 0.037)
Original publication
Early anaemia and prognosis after knee arthroplasty in nonagenarians admitted to ICU post surgery: a multicentre binational cohort study. Perioper Med (Lond). Published 10 February 2026. doi:10.
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