Cardiac arrest & resuscitation

Early prediction of long-term cognitive function, emotional distress, and health-related quality of life in cardiac arrest survivors

ResuscitationPublished Prospective cohort study

Authors' conclusion

MoCA and HADS scores during hospitalization relate to long-term cognitive and emotional outcomes after cardiac arrest.

Study context

Population
Patients who regained consciousness after cardiac arrest
Participants
100 patients
Outcome
Cognitive function (MoCA), emotional distress (HADS) and health-related quality of life (QoL) (EQ-5D-5L) predicted by early in-hospital measures (HADS, MoCA, Barthel Index, delirium, transient coma >24 h)
Follow-up
12 months
Methodological detailslongitudinal, multicentre
  • Longitudinal
  • Multicentre

Main finding

As reported in the abstract

Cognitive impairment at 12 months
20 %
Signs of anxiety at 12 months
8 %
Signs of depression at 12 months
10 %
Early Montreal Cognitive Assessment (MoCA) vs 12-month MoCA (borderline significant), β
0.21, p = 0.05
Early MoCA < 26 predicting cognitive impairment at 12 months, LR+
1.29 (95 % CI: 0.40-4.20)
Early MoCA < 26 predicting cognitive impairment at 12 months, LR-
0.60 (95 % CI: 0.18-1.94)
Early Hospital Anxiety and Depression Scale (HADS) vs 12-month HADS, β
0.47, 95 % CI: 0.33-0.60, p < 0.001
Age vs 12-month HADS (negative association), β
−0.10, 95 % CI: −0.18 to −0.02, p = 0.019

Observational data: associations, not effects.

Original publication

Early prediction of long-term cognitive function, emotional distress, and health-related quality of life in cardiac arrest survivors. Resuscitation. Published 4 July 2025. doi:10.1016/j.resuscitation.2025.110708

Composed by AI from the published abstract and checked against it. How Briefs are made →

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