Neuroanesthesia & neurocritical care

Temporal dynamics of neural synchrony and complexity of auditory EEG responses in post-hypoxic ischemic coma

ResuscitationPublished Mechanistic study

Authors' conclusion

Our findings provide novel insights on the optimal temporal window for assessing auditory functions in post-hypoxic ischemic coma.

Study context

Population
Unconscious patients in post-hypoxic ischemic coma after cardiac arrest
Comparison
Patients who regained consciousness vs those who did not
Outcome
Temporal evolution of neural synchrony (phase-locking value, PLV) and neural complexity of auditory-evoked EEG responses

Main finding

As reported in the abstract

  • Phase-locking value (PLV) predictive of chances to regain consciousness within the first 40 h post-cardiac arrest; predictive value diminished thereafter
  • PLV trajectories changed over time of coma in non-survivors; survivors had stable PLV
  • EEG response complexity not different between patients who regained consciousness and those who did not
  • EEG response complexity significantly diminished over time of coma, irrespective of outcome

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Temporal dynamics of neural synchrony and complexity of auditory EEG responses in post-hypoxic ischemic coma. Resuscitation. Published 7 February 2025. doi:10.1016/j.resuscitation.2025.110531

Composed by AI from the published abstract and checked against it. How Briefs are made →

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