Neuroanesthesia & neurocritical care

Early prediction of ventricular peritoneal shunt dependency in aneurysmal subarachnoid haemorrhage patients by recurrent neural network-based machine learning using routine intensive care unit data

J Clin Monit ComputPublished Retrospective cohort study

Authors' conclusion

RNN-based machine learning has the potential to predict VP shunt dependency on Day 4 after ictus in aSAH patients using routine data collected in the ICU.

Study context

Population
Patients with aneurysmal subarachnoid haemorrhage (aSAH) treated in the intensive care unit (ICU), November 2010 to May 2020
Participants
602 patients
Outcome
Prediction of ventriculoperitoneal (VP) shunt dependency
Methodological detailssingle-centre, machine learning prediction model (recurrent neural network (RNN)), More than 120 parameters analysed (routine neurocritical care data, vital signs, blood gas analyses); RNNs and gradient boosting machines evaluated
  • Single-centre
  • Machine learning prediction model (RNN)
  • More than 120 parameters analysed (routine neurocritical care data, vital signs, blood gas analyses); RNNs and gradient boosting machines evaluated

Main finding

As reported in the abstract

Prediction of VP shunt dependency by RNN
AUC-ROC after 1 day of ICU stay
0.77 (CI: 0.75-0.79)
AUC-ROC on Day 4
0.81 (CI: 0.79-0.84)
Accuracy on Day 4
76% (CI: 75.98-83.09%)
Sensitivity on Day 4
85% (CI: 83-88%)
Specificity on Day 4
74% (CI: 71-78%)

Observational data: associations, not effects.

Original publication

Early prediction of ventricular peritoneal shunt dependency in aneurysmal subarachnoid haemorrhage patients by recurrent neural network-based machine learning using routine intensive care unit data. J Clin Monit Comput. Published 21 March 2024. doi:10.1007/s10877-024-01151-4

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