Cardiac arrest & resuscitation
The effect of blood pressure on mortality following out-of-hospital cardiac arrest: a retrospective cohort study of the United Kingdom Intensive Care National Audit and Research Centre database
An erratum to this article was published (Crit Care, 4 May 2023 ↗)
Authors' conclusion
We found an association between hypotension and hypertension in the first 24 h in ICU and mortality following OHCA.
Study context
- Population
- Out-of-hospital Cardiac Arrest (OHCA) patients in UK ICUs (ICNARC Case Mix Programme), 1 January 2010 to 31 December 2019included in analysis
- Participants
- 32,349 patients
- Exposure
- Lowest and highest mean arterial pressure (MAP) and systolic blood pressure (SBP) in first 24 h of ICU care
- Outcome
- Hospital mortality (aOR for lowest and highest MAP and SBP in first 24 h of ICU care)
Methodological detailsnational registry (ICNARC Case Mix Programme), restricted cubic splines, adjusted
- National registry (ICNARC Case Mix Programme)
- Restricted cubic splines
- Adjusted
Main finding
As reported in the abstract
Hospital mortality
Hospital mortality
56.2%
Lowest recorded MAP associated with lowest mortality (mmHg)
60-63
Highest recorded MAP associated with lowest mortality (mmHg)
95-104
Observational data: associations, not effects.
Original publication
The effect of blood pressure on mortality following out-of-hospital cardiac arrest: a retrospective cohort study of the United Kingdom Intensive Care National Audit and Research Centre database. Crit Care. Published 5 January 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →