Perioperative medicine & outcomes

Effect of Enhanced Recovery After Surgery (ERAS) Programs on Perioperative Outcomes in Patients Undergoing Cardiac Surgery: A Systematic Review and Meta-analysis

J Cardiothorac Vasc AnesthPublished Systematic review and meta-analysis

Pooled result · Hospital LOSResult — go to the resultReduction in hospital stay 1.24 days 95% CI −1.67 to −0.82

Authors' conclusion

Although ERAS programs were associated with a reduction in hospital stay and no differences in mortality or atrial fibrillation, the quality of the evidence was very low.

Study context

Population
Adults undergoing elective cardiac surgery18 studies, 1 RCT
Participants
4,469 adults
Comparison
ERAS programs vs no ERAS in cardiac surgery
Outcome
Hospital LOS, mortality, AF and quality of life
Methodological detailsrandom-effects model, preregistered protocol (Open Science Framework), Quality of evidence very low
  • Random-effects model
  • Preregistered protocol (Open Science Framework)
  • Quality of evidence very low

Pooled result

Hospital LOS

Reduction in hospital stay

1.24 days

95% CI −1.67 to −0.82

P < 0.001

As reported in the abstract

Further pooled results

Mortality

No difference between the groups in mortality
OR 0.65 (95% CI 0.28, 1.48, p = 0.3)
  • Random-effects model
  • I2 = 0%

AF incidence

No difference between the groups in AF incidence
OR 0.77 (95% CI 0.57, 1.03, p = 0.08)
  • Random-effects model
  • I2 = 17%

Quality of life

Meta-analysis not feasible due to insufficient data

Original publication

Effect of Enhanced Recovery After Surgery (ERAS) Programs on Perioperative Outcomes in Patients Undergoing Cardiac Surgery: A Systematic Review and Meta-analysis. J Cardiothorac Vasc Anesth. Published 30 January 2025. doi:10.1053/j.jvca.2025.01.036

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