Paediatric anaesthesia & critical care

Effect of Intraoperative Hemispheric Synchronized Sounds on Depth of Anesthesia and Postoperative Pain in Children Undergoing Infraumbilical Surgery: A Double‐Blinded Randomized Controlled Trial

Paediatr AnaesthPublished Randomised controlled trial

Authors' conclusion

In our study, we observed that these sounds deepened the plane of anesthesia and had no evidence of a statistically significant difference in postoperative pain scores.

Study context

Population
Children aged 6 months to 7 years undergoing elective infraumbilical surgery under GA with caudal epidural block, tertiary care hospital in India2 equal groups
Participants
60 children
Comparison
Group-H vs Group-S
Primary endpoint
Depth of anesthesia (intraoperative BIS values, recorded every 5 min)
Methodological detailsdouble-blinded
  • Double-blinded

Primary result

As reported in the abstract

Intraoperative BIS values

Group-H

47.18

mean · SD 9.77

Group-S

54.32

mean · SD 6.15

P = 0.001

Further findings

OutcomeGroup-HGroup-SP value
Postoperative FLACC score · 60 minMedian0 (IQR 0–1)0 (IQR 0–1)P = 0.539
Postoperative FLACC score · 24 h00

Original publication

Effect of Intraoperative Hemispheric Synchronized Sounds on Depth of Anesthesia and Postoperative Pain in Children Undergoing Infraumbilical Surgery: A Double‐Blinded Randomized Controlled Trial. Paediatr Anaesth. Published 12 September 2026. doi:10.1002/pan.70307

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