Perioperative medicine & outcomes

Effect of multimodal home-based prehabilitation on objectively measured physical activity in patients undergoing elective cardiac or non-cardiac major surgery: secondary outcomes from a randomised controlled trial

Perioper Med (Lond)Published Secondary analysis of a randomised controlled trial

Authors' conclusion

Simple preoperative PA recommendations effectively improve steps per day in high-risk non-cardiac surgery patients.

Study context

Population
Patients ≥ 65 years awaiting elective cardiac or non-cardiac major surgery with a cardiopulmonary exercise test (CPET)-proven fitness deficit, single university hospital in Switzerland167 with complete data
Participants
200 patients
Comparison
Intervention vs Standard of care
Primary endpoint
Steps per day (open-source algorithm, wrist-worn accelerometer)
Follow-up
Preoperative period
Methodological detailstwo-arm parallel group, single-centre
  • Two-arm parallel group
  • Single-centre

Primary result

As reported in the abstract

Steps per day, non-cardiac patients (n = 107)

P = 0.042

Secondary outcomes

Overall Euclidean Norm Minus One (ENMO), non-cardiac patients

Higher in the intervention group but not statistically significant

Cardiac vs non-cardiac patients

Cardiac patients had overall higher physical activity (PA) levels and were younger; difference remained after adjusting for age

Steps per day vs overall ENMO

Steps per day correlated strongly with overall ENMO

Original publication

Effect of multimodal home-based prehabilitation on objectively measured physical activity in patients undergoing elective cardiac or non-cardiac major surgery: secondary outcomes from a randomised controlled trial. Perioper Med (Lond). Published 4 July 2025. doi:10.1186/s13741-025-00554-4

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