Hemodynamics, fluids & transfusion
Effect of Admission and Onset Time on the Prognosis of Patients With Cardiogenic Shock
Main finding · All-cause mortality, place of CS onsetResult — go to the resultHazard ratio 1.532 95% CI 0.990–2.371Authors' conclusion
Primary and secondary CS were associated with comparable, whereas primary out-of-hospital CS admitted during off-hours was associated with lower risk of all-cause mortality at 30 days.
Study context
- Population
- Consecutive patients with cardiogenic shock (CS) of any cause, 2019–202164% primary out-of-hospital CS
- Participants
- 273 patients
- Exposure
- Secondary CS vs Primary CS
- Outcome
- All-cause mortality
- Follow-up
- 30 days
Methodological detailsprospective registry, monocentric, consecutive patients
- Prospective registry
- Monocentric
- Consecutive patients
Main finding
All-cause mortality, place of CS onset
Hazard ratio
1.532
95% CI 0.990–2.371
P = 0.06
Secondary CS vs Primary CS
HR 1.532 (95% CI 0.990–2.371); P = 0.06
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| 30-day all-cause mortality, AMI-related CS (subgroup) | 2.087 (1.126–3.868) | P = 0.02 | |
| All-cause mortality, primary out-of-hospital CS by admission time · 30 daysOff-hours vs On-hours · irrespective of presence or absence of AMI | 0.497 (0.302–0.817) | P = 0.01 | |
| 0.20.5125Hazard ratio (log scale) |
Original publication
Effect of Admission and Onset Time on the Prognosis of Patients With Cardiogenic Shock. Chest. Published 12 August 2023. doi:10. 1016/ j. chest. 2023. 08. 011
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