Hemodynamics, fluids & transfusion

Effect of Admission and Onset Time on the Prognosis of Patients With Cardiogenic Shock

ChestPublished Prospective cohort study

Main finding · All-cause mortality, place of CS onsetResult — go to the resultHazard ratio 1.532 95% CI 0.990–2.371

Authors' conclusion

Primary and secondary CS were associated with comparable, whereas primary out-of-hospital CS admitted during off-hours was associated with lower risk of all-cause mortality at 30 days.

Study context

Population
Consecutive patients with cardiogenic shock (CS) of any cause, 2019–202164% primary out-of-hospital CS
Participants
273 patients
Exposure
Secondary CS vs Primary CS
Outcome
All-cause mortality
Follow-up
30 days
Methodological detailsprospective registry, monocentric, consecutive patients
  • Prospective registry
  • Monocentric
  • Consecutive patients

Main finding

All-cause mortality, place of CS onset

Hazard ratio

1.532

95% CI 0.990–2.371

P = 0.06

Secondary CS vs Primary CS
HR 1.532 (95% CI 0.990–2.371); P = 0.06

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeHR (95% CI)P value
30-day all-cause mortality, AMI-related CS (subgroup)2.087 (1.126–3.868)P = 0.02
All-cause mortality, primary out-of-hospital CS by admission time · 30 daysOff-hours vs On-hours · irrespective of presence or absence of AMI0.497 (0.302–0.817)P = 0.01

Original publication

Effect of Admission and Onset Time on the Prognosis of Patients With Cardiogenic Shock. Chest. Published 12 August 2023. doi:10.1016/j.chest.2023.08.011

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