Pediatric anesthesia & critical care
Effect of BIS-guided anesthesia on emergence delirium following general anesthesia in children: A prospective randomized controlled trial
Authors' conclusion
Individualization of the depth of general anesthesia with BIS monitoring is an effective method of preventing ED in children.
Study context
- Population
- Children aged 3–8 years undergoing endoscopic adenoidectomy under GAenrolled over 18 months
- Participants
- 163 children
- Comparison
- Intervention vs Control
- Interventionn = 86
- Controln = 77reference
- Primary endpoint
- Occurrence of ED during the PACU stay
- Follow-up
- PACU stay
Methodological detailsprospective, double-blind
- Prospective
- Double-blind
Primary result
As reported in the abstract
ED (PAED score >10) · entire PACU stay
P = 0.001
- Emergence delirium (ED) overall
- 23.3% (38/163)
Secondary outcomes
| Outcome | P value |
|---|---|
| PAED score · 10 min in PACULower PAED scores in the intervention group | P < 0.001 |
| PAED score · 30 min in PACULower PAED scores in the intervention group | P < 0.001 |
| Need for rescue treatment of EDDid not differ between groups | P = 0.067 |
Original publication
Effect of BIS-guided anesthesia on emergence delirium following general anesthesia in children: A prospective randomized controlled trial. Anaesth Crit Care Pain Med. Published 31 October 2023. doi:10.
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