Pediatric anesthesia & critical care

Electroencephalography and Anesthetic Depth in Children Under 2 Years of Age: A Prospective Observational Study

Paediatr AnaesthPublished Prospective observational study

Authors' conclusion

Processed EEG indices may exhibit unexpectedly elevated values during anesthesia maintenance in children under 2 years of age.

Study context

Population
Children aged 4–24 months undergoing GA
Participants
50 children
Exposure
False positives vs Emergence
Outcome
EEG spectral parameters associated with false positive elevations in processed EEG indices (BIS, patient state index (PSi)) and their differences from true positive elevations during emergence

Main finding

As reported in the abstract

False positives in processed EEG indices during maintenance
GroupValueShare of maintenance phase
False positives70%28%

False positives

Value70%
Share of maintenance phase28%
Delta band power decreased during false positives
269-174 dB
Theta band power decreased during false positives
115-97 dB
Spectral edge frequency elevated
19-22 Hz
Band power during false positives differed significantly from emergence: delta
52 dB
Band power during false positives differed significantly from emergence: theta
38 dB

Observational data: associations, not effects.

Original publication

Electroencephalography and Anesthetic Depth in Children Under 2 Years of Age: A Prospective Observational Study. Paediatr Anaesth. Published 26 December 2024. doi:10.1111/pan.15058

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