ICU sedation, delirium & recovery
Effect of Comprehensive Medication Management on Mortality in Critically Ill Patients
Main finding · Hospital mortalityResult — go to the resultEstimate −0.04 95% CI −0.06 to −0.03Authors' conclusion
The quantity of CCP-delivered CMM in the ICU is directly associated with reduced hospital mortality independent of patient characteristics and MRC.
Study context
- Population
- Consecutive adults admitted to an ICU ≥24 hours, Oregon Health Sciences University, June 2020–June 2023, with pharmacist intervention data
- Participants
- 10,441 ICU patients
- Exposure
- More critical care pharmacist (CCP) interventions vs CCP interventions less than 3
- Outcome
- Odds of hospital mortality
Methodological detailsobservational, propensity-matched, 1:1 matched cohort
- Observational
- Propensity-matched
- 1:1 matched cohort
Main finding
Hospital mortality
Estimate
−0.04
95% CI −0.06 to −0.03
P < 0.01
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Estimate (95% CI) | P value |
|---|---|---|
| ICU LOS | −2.77 (−2.98 to −2.56) | P < 0.01 |
Unadjusted mortality rate (whole cohort)
- Unadjusted mortality rate
- 11%
Original publication
Effect of Comprehensive Medication Management on Mortality in Critically Ill Patients. Crit Care Med. Published 6 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →