Perioperative medicine & outcomes

Effect of machine learning models on clinician prediction of postoperative complications: the Perioperative ORACLE randomised clinical trial

Br J AnaesthPublished Randomised controlled trial

Authors' conclusion

Clinician performance was not improved by machine learning assistance.

Study context

Population
Surgical patients aged ≥18 yr; predictions by anaesthesiologists and nurse anaesthetists providing remote telemedicine support89 clinicians
Participants
5,071 patients
Comparison
Clinician risk prediction with vs without machine learning predictions
Primary endpoint
AUROC for clinician predictions of 30-day all-cause mortality and AKI within 7 days, assisted vs unassisted
Methodological detailssingle-centre, prospective
  • Single-centre
  • Prospective

Primary result

As reported in the abstract

Assisted

0.793

Unassisted

0.780

Assisted vs UnassistedEstimate (95% CI)P value
AUROC for death
mean difference 0.013(−0.070 to 0.097)
P = 0.76
AUROC for AKI
difference 0.046(−0.003 to 0.091)
P = 0.06

Further findings

Weighted kappa

OutcomeAssistedUnassistedMean difference (95% CI)
Agreement of clinician predictions with models (weighted kappa), death0.750.620.13 (0.10–0.17)
Agreement of clinician predictions with models (weighted kappa), AKI0.790.540.25 (0.21–0.29)

Observed outcomes (all patients)

Died within 30 days of surgery
98 (2.2%)
Sustained acute kidney injury (AKI)
450 (11.1%)

Original publication

Effect of machine learning models on clinician prediction of postoperative complications: the Perioperative ORACLE randomised clinical trial. Br J Anaesth. Published 10 September 2024. doi:10.1016/j.bja.2024.08.004

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